The CX8180 has two serial interfaces: one with RS232 and one with RS485 physics. Both serial interfaces are on the D-sub socket. They are not bound to a particular protocol and can be used with the appropriate TwinCAT 3 functions for different serial communication protocols. E-bus or K-bus terminals can be attached as required; the CX8180 automatically recognizes the type of I/O system connected during the start-up phase. The control system is programmed with TwinCAT 3 via the Ethernet interface. TwinCAT 3 licenses must be ordered via the TwinCAT 3 price list.

https://www.beckhoff.com/vi-vn/products/ipc/embedded-pcs/cx8100-arm-cortex-a9/cx8180.html